HappyCross 16mg/ml (1×2.2ml)

HAppyCross™ is a cross-linked hyaluronic acid gel (IPN-Like technology). Cross-linking:

Ensures a gel-like rheological behaviour, maximizing then the mechanical properties of hyaluronic acid.
Increases the residence time of the gel in the joint cavity, preventing biodegradation from free radicals and enzymes.
Compared to the classic cross-linking technique, the IPN-Like technology, or InterPenetrated Cross-linked Networks, involves combining, inserting one into another, two monophasic hyaluronic acid networks previously purified and cross-linked which are mechanically independent. Interpenetration of Cross-linked Networks:

Optimizes the density of the chemical bonds while minimizing the use of reticulating agent (BDDE) within the monophasic gel, ensuring a longer-lasting effect of the product.
Preserves the partial independence of the inter-penetrated networks and guarantees the gel is supple and easy to inject into the joint.
HAppyCross™ also contains high concentration of mannitol (77mg/syringe).

Long-lasting effect: Mannitol is an anti-oxidant which protects hyaluronic acid chains from free radicals and limits their degradation, increasing then their residence time in the joint cavity.

Analgesic effect: Due to its free radical scavenging properties, mannitol also ensures local analgesic effect.

Stabilizer: because it is a thermal stabilizer, mannitol allows HAppyCross™ to guarantee a stability of its rheological properties all along its storage.